Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC486H781N125O133S7

DescriptionStandard

        MKLFLVLIILLFEVLTDGARLKKCFNNVTGYCRKKCKVGERYEIGCLSGKLCCINYEEEKEHVSFKKPHQHSGEKLSVQQDYIILPTVTIFTV
    

Molecular Weight10727.61 Da

Isoelectric Point (pI)8.76

Net Charge (pH 7.0)3.71

Net Charge (pH 7.4) 3.22

Charge Density (pH 7.0) 0.0399

GRAVY Index0.00

Hydrophobic Moment 0.62

Boman Index0.05

Instability Index13.15

Aliphatic Index 101.51

Aromaticity 0.0968

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4175.43

LogP -30.49

H-bond Donors 150.0

H-bond Acceptors 147.0

Rotatable Bonds 368.0

Heavy Atoms 751.0

Ring Count 14.0

Amide Bonds 98.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0240199 VERIFIED: NO

Provenance & Taxonomy

OrganismPongo abelii [Bacterium]

FamilyDefensin

Tax ID9601

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence

RECORD: Rec_0275343 VERIFIED: NO

Provenance & Taxonomy

OrganismPongo pygmaeus [Animal]

FamilyDefensin

Tax ID9600

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence