Peptide Database

Peptide NameNeuropeptide AF34

Function Ontology

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length11 amino acids

Chemical FormulaC60H99N15O17S

DescriptionStandard

        DSKLMDPLIRF
    

Molecular Weight1334.58 Da

Isoelectric Point (pI)5.96

Net Charge (pH 7.0)-0.24

Net Charge (pH 7.4) -0.44

Charge Density (pH 7.0) -0.0217

GRAVY Index-0.09

Hydrophobic Moment 0.57

Boman Index-0.05

Instability Index18.88

Aliphatic Index 106.36

Aromaticity 0.0909

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 528.28

LogP -2.78

H-bond Donors 18.0

H-bond Acceptors 18.0

Rotatable Bonds 44.0

Heavy Atoms 93.0

Ring Count 2.0

Amide Bonds 10.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0264793 VERIFIED: YES

Provenance & Taxonomy

OrganismAscaris suum [Animal]

FamilyNeuropeptide AF34

Tax ID6253

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide Neuromodulator

Half-LifeMammalian: 1.1 hour; Yeast: 3 min; E. coli: >10 hour

RECORD: Rec_0290920 VERIFIED: YES

Provenance & Taxonomy

OrganismAscaris suum [Animal]

FamilyFMRFamide related peptide

Tax ID6253

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Other ModsLeu4 oxidation

Bio-Activity Profile

Function

RFamide Neuropeptide Neuromodulator

RECORD: Rec_0297304 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/