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MYP_124104
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Basic Information
Scolopendrasin VII
Anticancer
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Standard
20 amino acids
C102H161N29O26S2
Standard
Sequence
FCTCNVKGFNAKNKRGIIYP
Physicochemical Analysis
2273.68 Da
9.70
3.74
3.50
0.1868
-0.28
0.38
-0.03
45.94
58.50
0.1500
1490.00
1615.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
917.12
-8.90
33.0
32.0
74.0
159.0
4.0
22.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0214665 VERIFIED: YES
Provenance & Taxonomy
Scolopendra subspinipes mutilans [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
C-terminal amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic Cytotoxic
human leukemia cells
MTS cell-viability assay
PMID25907065 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25907065/
RECORD: Rec_0249047 VERIFIED: YES
Provenance & Taxonomy
Scolopendra subspinipes mutilans [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
2-4
C-terminal amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
human leukemia cells
MTS cell-viability assay
PaperAnticancer activity of the antimicrobial peptide scolopendrasin VII derived from the centipede, Scolopendra subspinipes mutilans. PMID25907065
RECORD: Rec_0274208 VERIFIED: YES
Provenance & Taxonomy
Scolopendra subspinipes mutilans [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
C-terminal amidation
Bio-Activity Profile
Antimicrobial Antibacterial Growth-inhibition screening Me^x-nonsignificant antibacterial result
Escherichia coli TOP10
4.63 OD_ID (dimensionless)
Me^x pooled growth assay; OD_ID at 4.5 h; Wald test
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0374976 VERIFIED: YES
Provenance & Taxonomy
Scolopendra subspinipes mutilans [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
C-terminal amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
human leukemia cells
MTS cell-viability assay
PMID25907065 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25907065/
RECORD: Rec_0413802 VERIFIED: YES
Provenance & Taxonomy
Scolopendra subspinipes mutilans [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
C-terminal amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
human leukemia cells
MTS cell-viability assay
PMID25907065 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25907065/
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