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MYP_124061
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Basic Information
Hemocyte defensin Defh2, Cg-Defh2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
43 amino acids
C192H300N62O59S8
Standard
Sequence
GFGCPGDQYECNRHCRSIGCRAGYCDAVTLWLRCTCTGCSGKK
Physicochemical Analysis
4677.34 Da
8.51
2.77
2.39
0.0644
-0.36
0.57
-0.09
60.26
38.60
0.0930
8480.00
8980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1960.53
-25.82
79.0
71.0
150.0
321.0
7.0
44.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0003611 VERIFIED: YES
Provenance & Taxonomy
Crassostrea gigas [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Bacillus megaterium CIP 6620
0.03 μM
MIC
PMID20605792;22327168 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20605792/
RECORD: Rec_0061058 VERIFIED: YES
Provenance & Taxonomy
Magallana gigas [Animal]
Cg
29159
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PaperDev Comp Immunol. 2012 Jul;37(3-4):363-70 | http://www.ncbi.nlm.nih.gov/pubmed/22327168 PMID22327168 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22327168/
RECORD: Rec_0061543 VERIFIED: YES
Provenance & Taxonomy
Crassostrea gigas [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
M. lysodeikticus CIP 5345, Bacillus megaterium CIP 6620, Staphylococcus aureus CIP 103428, Staphylococcus aureus SG511, S. simulans 22, S. hemolyticus, M. maritypicum CIP 105733T, B. stationis CIP 101282
0.01-2 μM
MIC
PaperMolecular characterization of two isoforms of defensin from hemocytes of the oyster Crassostrea gigas.
RECORD: Rec_0062903 VERIFIED: NO
Provenance & Taxonomy
Crassostrea gigas [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
RECORD: Rec_0089948 VERIFIED: YES
Provenance & Taxonomy
Crassostrea gigas [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Vibrio aestuarianus CIP 102971
40 μM
MIC
PMID20605792;22327168 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20605792/
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