Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length72 amino acids

Chemical FormulaC376H605N103O97S8

DescriptionStandard

        MQLLFLFLTVMGLLAQGARVKKCWSTFGRCRENCKDSEVFYILCKEEGKCCVHPKYVRFKPKTLKNQLGTKN
    

Molecular Weight8376.98 Da

Isoelectric Point (pI)9.57

Net Charge (pH 7.0)8.53

Net Charge (pH 7.4) 8.15

Charge Density (pH 7.0) 0.1185

GRAVY Index-0.22

Hydrophobic Moment 0.73

Boman Index-0.06

Instability Index19.75

Aliphatic Index 77.08

Aromaticity 0.1111

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3270.99

LogP -26.14

H-bond Donors 120.0

H-bond Acceptors 115.0

Rotatable Bonds 287.0

Heavy Atoms 584.0

Ring Count 12.0

Amide Bonds 77.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0049717 VERIFIED: NO

Provenance & Taxonomy

OrganismUrocitellus parryii [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence