Peptide Database

Peptide NameHistidine-rich basic peptide

Function Ontology

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length43 amino acids

Chemical FormulaC211H324N80O58S

DescriptionStandard

        QVAQMHVWRAVNHDRNHGTGSGRHGRFLIRNRYRYGGGHLSDA
    

Molecular Weight4941.40 Da

Isoelectric Point (pI)11.62

Net Charge (pH 7.0)5.20

Net Charge (pH 7.4) 4.74

Charge Density (pH 7.0) 0.1208

GRAVY Index-1.07

Hydrophobic Moment 0.67

Boman Index-0.25

Instability Index17.35

Aliphatic Index 54.42

Aromaticity 0.0930

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2269.21

LogP -27.89

H-bond Donors 83.0

H-bond Acceptors 69.0

Rotatable Bonds 162.0

Heavy Atoms 350.0

Ring Count 10.0

Amide Bonds 47.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0238495 VERIFIED: YES

Provenance & Taxonomy

OrganismAplysia californica [Animal]

FamilyHistidine-rich basic peptide

Tax ID6500

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Bio-Activity Profile

Function

Neuropeptide Neuromodulator Myotropic

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour

RECORD: Rec_0408214 VERIFIED: YES