Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length446 amino acids

Chemical FormulaC2244H3515N597O640S12

DescriptionStandard

        TNPGFVVRITQAGLDYAHQQGISVLEKELAQLKLPDISGDFRIRHVGKVHYEISRLDLRSFHLPYSRITLVPNVGLQVAISNAFAEVDGDWRVKIHFIRDHGSFDLKVENIYIKINLKLGSDASGKPTIDTSDCNTRISNVRVLFSGKFGWLYNLFHSAIESRFRKILENEVCRNVVNSVRSELQPYLQTLPVTARIDAMTGTAGIDYSLVAPPTVTAQSLDVDLKGEFFSLEHRSTVPFPPLVLTLPPDHDRMVYFGASSYFFNTAGFAYHTAGVLVFEITDSMIPKDIDFHLNTSTFSAFVPQLEMMYPNMMMKLRLSAPSTPFLNIGPEGLSLKPVVDIQAYAILPDSSLAPLFLLSLVSNVSAVINMKSSHIAGNLNVGRYGGGAVQGGGWGDTSVRTLQSIMNIVASSILLPRLNERLEKGFPLPLPDRIQLYNTLVQFHQ
    

Molecular Weight49481.31 Da

Isoelectric Point (pI)6.87

Net Charge (pH 7.0)-0.45

Net Charge (pH 7.4) -1.41

Charge Density (pH 7.0) -0.0010

GRAVY Index0.06

Hydrophobic Moment 0.76

Boman Index0.12

Instability Index35.40

Aliphatic Index 100.72

Aromaticity 0.0942

Extinction Coeff. Reduced 37360.00

Extinction Coeff. Oxidized 37485.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0188607 VERIFIED: NO

Provenance & Taxonomy

OrganismAnhinga rufa [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria