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MYP_123948
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Basic Information
EeCentrocin 1 Chain A
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
30 amino acids
C143H228N50O36S
Standard
Sequence
GWWRRTVDKVRNAGRKVAGFASKACGALGH
Physicochemical Analysis
3255.72 Da
11.57
5.84
5.56
0.1945
-0.48
0.77
-0.13
35.30
58.67
0.1000
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1413.99
-15.52
54.0
44.0
107.0
230.0
6.0
30.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0007118 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID32403086 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32403086/
RECORD: Rec_0054639 VERIFIED: YES
Provenance & Taxonomy
Echinus esculentus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Saccharomyces cerevisiae
50 μM
MIC
PMID27007817 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27007817/
RECORD: Rec_0062000 VERIFIED: YES
Provenance & Taxonomy
Echinus esculentus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa ATCC 27853
1.56 μM
MIC
PMID27007817 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27007817/
RECORD: Rec_0072908 VERIFIED: YES
Provenance & Taxonomy
Echinus esculentus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
DSM 19880
3.13 μM
MIC
PMID27007817 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27007817/
RECORD: Rec_0075833 VERIFIED: YES
Provenance & Taxonomy
Echinus esculentus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus epidermidis ATCC 35984
3.13 μM
MIC
PMID27007817 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27007817/
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