Peptide Database

Peptide NameBuffalo hepcidin

Function Ontology

—

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC112H180N34O31S9

DescriptionStandard

        DTHFPICVFCCSCCRKGMCGLCCRT
    

Molecular Weight2787.42 Da

Isoelectric Point (pI)8.22

Net Charge (pH 7.0)1.77

Net Charge (pH 7.4) 1.40

Charge Density (pH 7.0) 0.0707

GRAVY Index0.63

Hydrophobic Moment 0.41

Boman Index0.07

Instability Index13.77

Aliphatic Index 42.80

Aromaticity 0.0800

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1029.42

LogP -11.92

H-bond Donors 45.0

H-bond Acceptors 43.0

Rotatable Bonds 87.0

Heavy Atoms 186.0

Ring Count 4.0

Amide Bonds 24.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0078276 VERIFIED: YES

Provenance & Taxonomy

OrganismPhyseter macrocephalus [Animal]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)