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MYP_123900
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Basic Information
Gaegurin-LK2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
24 amino acids
C116H202N28O27S3
Standard
Sequence
FLGPIIKMATGILPTAICKGLKKC
Physicochemical Analysis
2517.21 Da
9.70
3.74
3.50
0.1557
0.89
0.59
0.33
26.67
122.08
0.0417
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
859.58
-4.05
31.0
34.0
84.0
174.0
3.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0148597 VERIFIED: YES
Provenance & Taxonomy
Limnonectes kuhlii [Animal]
Gaegurin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis
20 μg/mL
MIC
PMID23054029 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23054029/
RECORD: Rec_0217024 VERIFIED: YES
Provenance & Taxonomy
Limnonectes kuhlii [Animal]
Gaegurin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Rabbit RBC
100 μg/mL
Hemolysis
PMID23054029 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23054029/
RECORD: Rec_0240288 VERIFIED: YES
Provenance & Taxonomy
Limnonectes kuhlii [Animal]
Gaegurin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
18-24
Bio-Activity Profile
Antimicrobial Antifungal
Pseudomonas aeruginosa ATCC 27853
5 μg/mL
MIC
PaperFive novel antimicrobial peptides from the Kuhl's wart frog skin secretions, Limnonectes kuhlii.
RECORD: Rec_0255740 VERIFIED: YES
Provenance & Taxonomy
Limnonectes kuhlii [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0274470 VERIFIED: YES
Provenance & Taxonomy
Limnonectes kuhlii [Animal]
Gaegurin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
18-24
Bio-Activity Profile
Antimicrobial Antifungal
Staphylococcus aureus ATCC 2592
2.5 μg/mL
MIC
PaperFive novel antimicrobial peptides from the Kuhl's wart frog skin secretions, Limnonectes kuhlii.
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