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MYP_123874
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Basic Information
Unnamed
Immunology ▸ Adverse immune reactivity ▸ Allergenicity ▸ Allergen-specific CD4 T-cell epitope
Immunology ▸ Epitope/vaccine antigen ▸ T-cell epitope ▸ Allergen-specific CD4 T-cell epitope
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Standard
15 amino acids
C70H126N22O23
Standard
Sequence
KTLTNKLKAAEARAE
Physicochemical Analysis
1643.88 Da
9.70
1.77
1.55
0.1179
-0.89
0.42
-0.32
3.78
78.67
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
768.83
-8.63
27.0
25.0
59.0
115.0
0.0
15.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0156815 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anti-inflammatory
PaperGupta S, Sharma AK, Shastri V, Madhu MK, Sharma VK. Prediction of anti-inflammatory proteins/peptides: an insilico approach. J Transl Med. 2017;15:7. PMID:28057002. https://pubmed.ncbi.nlm.nih.gov/28057002/ PMID28057002 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28057002/
RECORD: Rec_0366697 VERIFIED: YES
Provenance & Taxonomy
Penaeus aztecus [Animal]
Tropomyosin
6690.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anti-inflammatory Allergen-specific CD4 T-cell epitope
Human CD4 T cells (shrimp-allergic subjects)
MHC-peptide binding assay; CFSE dilution; tritiated-thymidine incorporation; cytokine release assay
PaperEugene V Ravkov et al. Identification and validation of shrimp-tropomyosin specific CD4 T cell epitopes. Hum Immunol. 2013. PMID: 23993987. https://pubmed.ncbi.nlm.nih.gov/23993987/ ; https://pmc.ncbi.nlm.nih.gov/articles/PMC3870591/ PMID23993987 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23993987/