Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length120 amino acids

Chemical FormulaC610H1004N170O165S5

DescriptionStandard

        MLAVLKYLNTIVVQYGSGPRLIEENRWNNLNLLLNLTSLSRQLGMADMQQKLNSIQVPDFSGKKRVSPIGKVQYNFIRVLKVGIPKSSVDLVPGTGVRMSIGDAFISLNGRWKVKYLRIM
    

Molecular Weight13519.86 Da

Isoelectric Point (pI)10.48

Net Charge (pH 7.0)10.50

Net Charge (pH 7.4) 10.26

Charge Density (pH 7.0) 0.0875

GRAVY Index0.01

Hydrophobic Moment 0.67

Boman Index0.05

Instability Index29.22

Aliphatic Index 112.75

Aromaticity 0.0750

Extinction Coeff. Reduced 16960.00

Extinction Coeff. Oxidized 16960.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5457.29

LogP -47.81

H-bond Donors 189.0

H-bond Acceptors 181.0

Rotatable Bonds 460.0

Heavy Atoms 950.0

Ring Count 16.0

Amide Bonds 134.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0335699 VERIFIED: NO

Provenance & Taxonomy

OrganismPundamilia nyererei [Bacterium]

FamilyBPI

Tax ID303518

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin Non-hemolytic

TargetGram-negative bacteria

MethodQualitative functional evidence