Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length76 amino acids

Chemical FormulaC406H606N96O111S

DescriptionStandard

        MEVKYSAFGRFDVSPIQQTLNFLASLFLFPAANAKLQAGFSLPLTRDISFYDFILQPYKNYLLLGANIHYGLESEN
    

Molecular Weight8639.80 Da

Isoelectric Point (pI)5.56

Net Charge (pH 7.0)-1.41

Net Charge (pH 7.4) -1.69

Charge Density (pH 7.0) -0.0185

GRAVY Index0.16

Hydrophobic Moment 0.50

Boman Index0.20

Instability Index60.02

Aliphatic Index 98.95

Aromaticity 0.1711

Extinction Coeff. Reduced 7450.00

Extinction Coeff. Oxidized 7450.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3315.80

LogP -24.01

H-bond Donors 111.0

H-bond Acceptors 112.0

Rotatable Bonds 277.0

Heavy Atoms 614.0

Ring Count 18.0

Amide Bonds 84.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0007524 VERIFIED: NO

Provenance & Taxonomy

OrganismPhascolarctos cinereus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria