Peptide Database

Peptide NameAldesleukin

Function Ontology

Anticancer

Immunology ▸ Immune modulation ▸ Immunostimulatory activity

Standard StatusStandard

Sequence Length134 amino acids

Chemical FormulaC698H1129N179O204S8

DescriptionStandard

        MAPTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHLRPRDLISNINVIVLELKGSETTFMCEYADETATIVEFLNRWITFCQSIISTLT
    

Molecular Weight15549.03 Da

Isoelectric Point (pI)6.83

Net Charge (pH 7.0)-0.24

Net Charge (pH 7.4) -0.70

Charge Density (pH 7.0) -0.0018

GRAVY Index-0.16

Hydrophobic Moment 0.66

Boman Index0.03

Instability Index53.35

Aliphatic Index 102.61

Aromaticity 0.0746

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10095.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6216.69

LogP -52.07

H-bond Donors 214.0

H-bond Acceptors 215.0

Rotatable Bonds 531.0

Heavy Atoms 1089.0

Ring Count 19.0

Amide Bonds 148.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0218585 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]; Escherichia coli [Bacterium]

FamilyPeptide/protein therapeutic

Tax ID9606;562

Structure & Mods

Configlinear peptide/protein therapeutic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Immunostimulatory Anticancer Interleukin-2

Half-Life0.22-1.42 h