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MYP_123757
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Basic Information
Diketopiperazine (preWF)
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Antimalarial
Antiparasitic ▸ Antiprotozoal ▸ Antimalarial ▸ Anti-Plasmodium
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Antiviral
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
not Standard
2 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
XF
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0174975 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Boc-Orn(Z)=tert-Butyloxycarbonyl
Methyl ester
Z=Ornithine
Bio-Activity Profile
Anticancer Antibacterial Antiviral Antiparasitic Antimicrobial Antifungal Antiplasmodial
PaperParaPep: a web resource for experimentally validated antiparasitic peptide sequences and their structures PMID24923818 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24923818/
RECORD: Rec_0217057 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
cyclic peptide; DSSP H 0.0%, E 0.0%, T 0.0%, C 100.0% [Cyclic]
residue-level stereochemical modification [Mixed]
None
None
Sar
Bio-Activity Profile
Anticancer Antibacterial Antiviral Antiparasitic Antimicrobial Antifungal Antiplasmodial
PaperParaPep: a web resource for experimentally validated antiparasitic peptide sequences and their structures PMID24923818 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24923818/
RECORD: Rec_0251817 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
E1: gamma-glutamyl
Bio-Activity Profile
-
RECORD: Rec_0346641 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
diketopiperazine
32630
Structure & Mods
cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Antiviral Anticancer Antimalarial Antiparasitic
Plasmodium berghei ANKA 2.34
2.26 μM
IC50; Microscopy
PMID23084276 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23084276/
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Showing 4 records · Page 2 of 2