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MYP_123750
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Basic Information
RNase 3 (1-36)[P3,Q4,L18,N19,P20,C23DEL], RN3(5-17P22-36)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
30 amino acids
C171H262N56O39S
Standard
Sequence
RPFTRAQWFAIQHISPRTIAMRAINNYRWR
Physicochemical Analysis
3758.33 Da
12.00
5.85
5.59
0.1949
-0.67
0.48
-0.20
60.23
65.33
0.1667
12490.00
12490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1574.58
-13.05
58.0
47.0
117.0
267.0
10.0
33.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0104591 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
MRC-5
150 μM
IC50
PaperPubMed PMID: 29763807 PMID29763807 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29763807/
RECORD: Rec_0114721 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Acinetobacter baumannii ATCC 15308
10 μM
MIC
PMID35203595 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35203595/
RECORD: Rec_0135531 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
Hep-G2
74.43±1.91 μM
IC50
PaperPubMed PMID: 29763807 PMID29763807 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29763807/
RECORD: Rec_0184278 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PaperPubMed PMID: 29763807 PMID29763807 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29763807/
RECORD: Rec_0256057 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Sheep erythrocytes
50 %
Hemolysis
PaperPubMed PMID: 29763807 PMID29763807 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29763807/
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