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MYP_123702
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Basic Information
L12
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
18 amino acids
C104H167N33O19S
Standard
Sequence
PAWRKAFRWAKRMLKKAA
Physicochemical Analysis
2215.71 Da
12.00
6.95
6.89
0.3864
-0.83
0.96
-0.33
57.01
49.44
0.1667
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
865.39
-4.04
34.0
27.0
74.0
157.0
6.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0121563 VERIFIED: YES
Provenance & Taxonomy
Litoria aurea [Animal]
Lactoferrin-derived peptide
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Meth A
7.9 μM
IC50
PaperEnhanced antitumor activity and selectivity of lactoferrin-derived peptides PMID12366526 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12366526/
RECORD: Rec_0132279 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
RECORD: Rec_0149366 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
HT-29
25 μM
IC50
PaperPubMed PMID: 12366526 PMID12366526 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12366526/
RECORD: Rec_0168904 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Lactoferrin-derived peptides
9913.0
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Antimicrobial
HT-29 (colon cancer)
25 μM
IC50
PaperEnhanced antitumor activity and selectivity of lactoferrin-derived peptides | https://pubmed.ncbi.nlm.nih.gov/12366526/ PMID12366526 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12366526/
RECORD: Rec_0244040 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
Fibroblas
31 μM
IC50
PaperPubMed PMID: 12366526 PMID12366526 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12366526/
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