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MYP_123693
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Basic Information
Antimicrobial peptide GP-19 (GP-19)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
19 amino acids
C75H123N19O23
Standard
Sequence
GPVGLLSSPGSLPPVGGAP
Physicochemical Analysis
1658.89 Da
5.53
-0.24
-0.44
-0.0126
0.48
0.17
0.44
86.51
97.37
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
603.86
-7.74
18.0
23.0
43.0
117.0
5.0
18.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0313886 VERIFIED: YES
Provenance & Taxonomy
Xenorhabdus budapestensis [Bacterium]
Defensin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive
Bacillus subtilis
19.04±0.2 mm
agar diffusion inhibition-zone assay
PMID22497806 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22497806/
RECORD: Rec_0317253 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 52.6%, C 47.4% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial Antifungal
PaperCAMP: Collection of sequences and structures of antimicrobial peptides PMID24265220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24265220/
RECORD: Rec_0320698 VERIFIED: YES
Provenance & Taxonomy
Xenorhabdus budapestensis [Bacterium]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Verticillium dahliae
17.54 μg/mL
EC50
PaperPubMed PMID: 22497806 PMID22497806 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22497806/
RECORD: Rec_0320813 VERIFIED: YES
Provenance & Taxonomy
Xenorhabdus budapestensis [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Fusarium graminearum
12.04±0.87 mm
fungal growth inhibition (colony-diameter assay)
PMID22497806 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22497806/
RECORD: Rec_0355325 VERIFIED: YES
Provenance & Taxonomy
Xenorhabdus budapestensis [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anti-Gram-negative Anti-Gram-positive Non-hemolytic
P. wickerhamii
agar diffusion and fungal growth inhibition assays
PMID22497806 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22497806/
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