Peptide Database

Peptide NameColicin-D

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length723 amino acids

Chemical FormulaC3385H5294N920O1060S19

DescriptionStandard

        MTRIMSTMLYIHPPHGCCAFKMEINMSDNETVPTQGVDYGHTIVGWPVRPKWGQPDAGASIGINPDFDPVTGNGWLPEEDGYHHDLPAGTPADVQSAINQVKQAGGLMSVDLRKLRPAAGYPWDQTVAWDPVFVYFPAKAVSDSDLSAGSLPETVPVHSRIQDDVHDGAQFISVTGSGSQPYNLPVIKATPTPRGPYYTIGHLPGPMGPYTFTFNANAPHSEMHFARDEEKVSALHPAGFTVGANTTDCIVVFPEGSGLEPLYFSMTVILPEGPLKQRQEEENQARAKADAEAKAKAEAEAKAKAEAEAKAKAEREALFTRAGVVPAPTYTPEMVKSAEAALGAAGVMVLGQTPGAMQLSVAGGGVLTATGEVLSSLGAAVGRAIASLGATATAGTAGPMVAAASAILFPPAAGEGSDRVPGRDLNAMFALNAQLLAGQDVKIEPGATSVNLPERGHLVNSNGQMALQLLKTGDTLPAAVPVLNAVRDAATGLDRITVPAVAGAPERTILVNPAPSPAAPSDTASPPPSVPVTPVHTGTEIKPVETITVTTTPAADIGGLQDFIYWRPDAAGTGVEPIYVILSSPYGETNAKGKYSGRDYNSDKAGGPIQDLYWKTATIDREGVDKVKLHTGRFGESPENVVMIDRLEKILKGELQPTDTDKRFYTHEVRELERYRALGIADGTVPENDYEVWNNTHTATLEDYKLSSDETLLYTPEALNSQN
    

Molecular Weight76447.01 Da

Isoelectric Point (pI)4.95

Net Charge (pH 7.0)-29.01

Net Charge (pH 7.4) -30.26

Charge Density (pH 7.0) -0.0401

GRAVY Index-0.25

Hydrophobic Moment 0.77

Boman Index0.08

Instability Index35.36

Aliphatic Index 78.06

Aromaticity 0.0650

Extinction Coeff. Reduced 76780.00

Extinction Coeff. Oxidized 76905.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0100166 VERIFIED: NO

Provenance & Taxonomy

OrganismSalmonella muenchen [Bacterium]

FamilyColicin/Bacteriocin

Tax ID28901

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Non-hemolytic

TargetEscherichia coli (Gram-negative)

MethodQualitative functional evidence