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MYP_123631
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Basic Information
TP-biot1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antiviral
Antiviral ▸ Anti-Herpesvirus ▸ Anti-HSV
Antiviral ▸ Anti-HIV
Antiviral ▸ Anti-Influenza virus ▸ Anti-Influenza
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
27 amino acids
C134H226N34O33
Standard
Sequence
GWTLNSAGYLLGKINLKALAALAKKIL
Physicochemical Analysis
2841.44 Da
10.18
3.76
3.54
0.1391
0.63
0.58
0.30
0.04
148.52
0.0741
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1086.66
-6.28
38.0
37.0
97.0
201.0
3.0
28.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0312938 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Salmonella enterica subsp. enterica serovar Enteritidis ATCC 13076
1.6 μM
MBC
PMID22853904;32153547 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22853904/
RECORD: Rec_0355738 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Broad-spectrum antiviral peptide
32630.0
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antiviral Anti-HIV Anti-HSV Anti-Influenza
HSV, HIV, Influenza A Virus, H5 Avian Influenza Virus
PaperMethod of inhibiting influenza infection with antiviral peptides Evidence URLhttps://patents.google.com/patent/US7432045B2/en PatentUS 7432045 B2
RECORD: Rec_0357038 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 59.3%, E 0.0%, T 29.6%, C 11.1% [Linear]
canonical L-amino-acid peptide [L]
Bromoacetylation
Amidation
Bio-Activity Profile
Drug Delivery Vehicle Cell-penetrating peptide
PaperCPPsite: a curated database of cell penetrating peptides PMID22403286 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22403286/
RECORD: Rec_0357626 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Transportan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Fluorescein/FITC labeling
Amidation
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PaperTranslocation of cell-penetrating peptides across the plasma membrane is controlled by cholesterol and microenvironment created by membranous proteins PMID25016968 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25016968/
RECORD: Rec_0369656 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Transportan
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Biotinylation
None
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PaperDeletion analogues of transportan PMID10930519 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10930519/
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