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MYP_123631
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Basic Information
TP-biot1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antiviral
Antiviral ▸ Anti-Herpesvirus ▸ Anti-HSV
Antiviral ▸ Anti-HIV
Antiviral ▸ Anti-Influenza virus ▸ Anti-Influenza
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
27 amino acids
C134H226N34O33
Standard
Sequence
GWTLNSAGYLLGKINLKALAALAKKIL
Physicochemical Analysis
2841.44 Da
10.18
3.76
3.54
0.1391
0.63
0.58
0.30
0.04
148.52
0.0741
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1086.66
-6.28
38.0
37.0
97.0
201.0
3.0
28.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0255484 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Membrane-active peptide
PaperFerrer - Miralles N., Vazquez E., Villaverde A.. Membrane-active peptides fro non-viral gene therapy: making the safest easier. Trends Biotechnol., 2008, 26, 5, 267-275.
RECORD: Rec_0269975 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Drug Delivery Vehicle Cell-penetrating peptide
PaperCPPsite: a curated database of cell penetrating peptides PMID22403286 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22403286/
RECORD: Rec_0290259 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa DSM 1117
86 μM
MIC
PMID22853904;32153547 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22853904/
RECORD: Rec_0311688 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Transportan
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Fluorescein/FITC labeling
Amidation
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PMID25511292 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25511292/
RECORD: Rec_0312234 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiviral
Evidence URLhttps://patents.google.com/patent/US20050130884A1/en PatentUS 2005/0130884 A1
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