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MYP_123631
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Basic Information
TP-biot1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antiviral
Antiviral ▸ Anti-Herpesvirus ▸ Anti-HSV
Antiviral ▸ Anti-HIV
Antiviral ▸ Anti-Influenza virus ▸ Anti-Influenza
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
27 amino acids
C134H226N34O33
Standard
Sequence
GWTLNSAGYLLGKINLKALAALAKKIL
Physicochemical Analysis
2841.44 Da
10.18
3.76
3.54
0.1391
0.63
0.58
0.30
0.04
148.52
0.0741
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1086.66
-6.28
38.0
37.0
97.0
201.0
3.0
28.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0112486 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Transportan
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
None
Amidation
Fluorescein coupled to Lys13
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PaperTranslocation of cell-penetrating peptides across the plasma membrane is controlled by cholesterol and microenvironment created by membranous proteins PMID25016968 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25016968/
RECORD: Rec_0115201 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Transportan/TP10
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Biotinylation
None
N-term detail: Biotinylation
Bio-Activity Profile
Cell-penetrating peptide
Human bowes melanoma cells
Cellular uptake assay
PMID10930519 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10930519/
RECORD: Rec_0115384 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Broad-spectrum antiviral peptide
32630.0
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antiviral Anti-HIV Anti-HSV
HSV
PaperPharmacologically active antiviral peptides and methods of their use Evidence URLhttps://patents.google.com/patent/US20050130884/en PatentUS 20050130884
RECORD: Rec_0142891 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Acinetobacter baumannii ATCC 17978
3.1 μM
MBC
PMID22853904;32153547 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22853904/
RECORD: Rec_0165212 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli ATCC 8739
3.1 μM
MIC
PMID22853904;32153547 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22853904/
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