Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length186 amino acids

Chemical FormulaC931H1469N249O255S9

DescriptionStandard

        PMTPPMAHEPMLLLAVTEFVANSAAFTYFTAGALHRTISSDTLPRQFPLQLRTKSMEVFSPQLQERYPDQPMELHLWARQQPLLSCHPDALHGTLFSSAEAFVVLPNATRVPAFLLNIDANVTGKPTITRNRLGGTVRLTGLVPDPELPQGLPVLQVKRLETVLKFGLWLFGVPQANSKCCPCPVP
    

Molecular Weight20518.72 Da

Isoelectric Point (pI)8.59

Net Charge (pH 7.0)2.38

Net Charge (pH 7.4) 1.98

Charge Density (pH 7.0) 0.0128

GRAVY Index0.03

Hydrophobic Moment 0.55

Boman Index0.12

Instability Index49.54

Aliphatic Index 92.80

Aromaticity 0.0753

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7872.64

LogP -90.14

H-bond Donors 267.0

H-bond Acceptors 271.0

Rotatable Bonds 641.0

Heavy Atoms 1444.0

Ring Count 43.0

Amide Bonds 201.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0313471 VERIFIED: NO

Provenance & Taxonomy

OrganismRhabdornis inornatus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria