Peptide Database

Peptide NameLysozyme (EC 3.2.1.17)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Standard StatusStandard

Sequence Length171 amino acids

Chemical FormulaC827H1329N243O236S9

DescriptionStandard

        MNPSIVKRCLVGAVLAIAATLPGFQQLHTSVEGLKLIADYEGCRLQPYQCSAGVWTDGIGNTSGVIPGKTITERQAAEGLISNVLRVERALERCVKQQPPQKVYDATVSFAFNVGTGNACSSTLVKLLNQRRWAEACRQLPRWVYVKGVFNQGLDNRRAREMAWCFKGAGL
    

Molecular Weight18740.47 Da

Isoelectric Point (pI)9.47

Net Charge (pH 7.0)8.53

Net Charge (pH 7.4) 8.13

Charge Density (pH 7.0) 0.0499

GRAVY Index-0.09

Hydrophobic Moment 0.95

Boman Index0.02

Instability Index35.13

Aliphatic Index 89.53

Aromaticity 0.0760

Extinction Coeff. Reduced 27960.00

Extinction Coeff. Oxidized 28335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7744.63

LogP -81.68

H-bond Donors 276.0

H-bond Acceptors 255.0

Rotatable Bonds 619.0

Heavy Atoms 1315.0

Ring Count 25.0

Amide Bonds 189.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0124128 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia coli [Bacterium]

FamilyLysozyme

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase

PaperSKESA: strategic k-mer extension for scrupulous assemblies; Cumulative acquisition of pathogenicity islands has shaped virulence potential and contributed to the emergence of LEE-negative Shiga toxin-producing Escherichia coli strains PMID30286803;30924410 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/?term=30286803+OR+30924410