Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length152 amino acids

Chemical FormulaC751H1176N216O220S7

DescriptionStandard

        MVSKVQFNPRSRTDAIFVHCSATKPDMDIGVETIRMWHKQQGWLDVGYHFIIKRDGTVEEGRPVNVVGSHVKDWNSKSVGVCLVGGINAKGQFEANFTPAQMNSLRNKLADLKALYPQAEIKAHHDVAPKACPSFDLQRWLTTNELITSDNG
    

Molecular Weight16975.14 Da

Isoelectric Point (pI)8.47

Net Charge (pH 7.0)2.01

Net Charge (pH 7.4) 1.41

Charge Density (pH 7.0) 0.0132

GRAVY Index-0.39

Hydrophobic Moment 0.57

Boman Index-0.01

Instability Index39.77

Aliphatic Index 77.57

Aromaticity 0.0789

Extinction Coeff. Reduced 24980.00

Extinction Coeff. Oxidized 25105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7021.26

LogP -71.96

H-bond Donors 242.0

H-bond Acceptors 235.0

Rotatable Bonds 561.0

Heavy Atoms 1194.0

Ring Count 29.0

Amide Bonds 167.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0152849 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia phage TM1 [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic