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MYP_123565
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Basic Information
Penaeidin-4a (Pen-4a; shrimps, Arthropods, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
47 amino acids
C230H358N70O62S6
Standard
Sequence
HSSGYTRPLPKPSRPIFIRPIGCDVCYGIPSSTARLCCFRYGDCCHR
Physicochemical Analysis
5288.12 Da
9.15
4.87
4.47
0.1037
-0.27
0.76
-0.07
44.85
58.09
0.1064
4470.00
4845.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2080.86
-22.56
81.0
75.0
159.0
368.0
13.0
46.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0004946 VERIFIED: YES
Provenance & Taxonomy
Litopenaeus vannamei [Animal]
Penaeidin
6689
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
23-37, 26-44, 38-45
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Salmonella thyphimurium
50 μM
MIC
PMID12242595;15084144 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12242595/
RECORD: Rec_0045958 VERIFIED: YES
Provenance & Taxonomy
Litopenaeus vannamei [Animal]
Penaeidin
6689
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
23-37, 26-44, 38-45
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Micrococcus luteus
1.9-2.92 μM
MIC
PMID12242595;15084144 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12242595/
RECORD: Rec_0066438 VERIFIED: YES
Provenance & Taxonomy
Litopenaeus vannamei [Animal]
Penaeidin
6689
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
23-37, 26-44, 38-45
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Fusarium oxysporum
0.84-1.26 μM
MIC
PMID12242595;15084144 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12242595/
RECORD: Rec_0112036 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0114482 VERIFIED: YES
Provenance & Taxonomy
Litopenaeus vannamei [Animal]
Penaeidin
6689
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
23-37, 26-44, 38-45
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Saphylococcus aureus
50 μM
MIC
PMID12242595;15084144 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12242595/
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