MYP_123561
kaliotoxin
Membrane / Ion-channel modulation
▸
Ion channel modulation
Venom / Toxin
▸
General toxin
▸
Toxin-related activity
not Standard
38 amino acids
-
contains X representing unresolved or non-standard residue
GVEXNVKCSGSPQCLKPCKDAGMRFGKCMNRKCHCXPK
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Amino Acid Composition
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0397692
VERIFIED: YES
Provenance & Taxonomy
not reported [other]
GtoPdb peptide ligand
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
stereochemistry not specified [Other]
reported in GtoPdb PTM annotation
C-terminal lysine residue undergoes amidation; disulphide bond formation between cysteine residues at positions 7 and 47, 13 and 32, and 17 and 34.
Bio-Activity Profile
Ion channel modulation
Toxin-related activity
KCa1.1 (Human); Kv1.1 (Mouse); Kv1.3 (Rat)
20 nM
IC50