Peptide Database

Peptide NameCobatoxin 1

Function Ontology

Annotation / Sequence feature ▸ Nuclear export signal

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity

Membrane / Ion-channel modulation ▸ Ion channel inhibition

Membrane / Ion-channel modulation ▸ Potassium channel modulation ▸ Potassium channel inhibitor

Venom / Toxin ▸ General toxin ▸ Toxin

Venom / Toxin ▸ Toxin

Standard StatusStandard

Sequence Length32 amino acids

Chemical FormulaC156H250N50O45S6

DescriptionStandard

        AVCVYRTCDKDCKRRGYRSGKCINNACKCYPY
    

Molecular Weight3738.35 Da

Isoelectric Point (pI)9.24

Net Charge (pH 7.0)5.73

Net Charge (pH 7.4) 5.44

Charge Density (pH 7.0) 0.1791

GRAVY Index-0.79

Hydrophobic Moment 0.74

Boman Index-0.35

Instability Index49.22

Aliphatic Index 36.56

Aromaticity 0.1250

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1590.47

LogP -18.39

H-bond Donors 64.0

H-bond Acceptors 57.0

Rotatable Bonds 122.0

Heavy Atoms 257.0

Ring Count 5.0

Amide Bonds 33.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0000037 VERIFIED: NO

Provenance & Taxonomy

OrganismCentruroides noxius [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Toxin

RECORD: Rec_0119662 VERIFIED: YES