Peptide Database

Peptide NameAlefacept

Function Ontology

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Immunology ▸ Immunomodulation ▸ Immunosuppressive

Immunology ▸ Inflammation modulation ▸ Anti-inflammatory

Standard StatusStandard

Sequence Length242 amino acids

Chemical FormulaC1215H1901N319O369S19

DescriptionStandard

        CFSQQIYGVVYGNVTFHVPSNVPLKEVLWKKQKDKVAELENSEFRAFSSFKNRVYLDTVSGSLTIYNLTSSDEDEYEMESPNITDTMKFFLYVLESLPSPTLTCALTNGSIEVQCMIPEHYNSHRGLIMYSWDCPMEQCKRNSTSIYFKMENDLPQKIQCTLSNPLFNTTSSIILTTCIPSSGHSRHRYALIPIPLAVITTCIVLYMNGILKCDRKPDRTNSNRVEPKSCDKTHTCPPCPAP
    

Molecular Weight27490.24 Da

Isoelectric Point (pI)6.64

Net Charge (pH 7.0)-0.81

Net Charge (pH 7.4) -1.56

Charge Density (pH 7.0) -0.0033

GRAVY Index-0.29

Hydrophobic Moment 0.66

Boman Index0.01

Instability Index43.56

Aliphatic Index 77.27

Aromaticity 0.0909

Extinction Coeff. Reduced 27390.00

Extinction Coeff. Oxidized 28140.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0373300 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]; Cricetulus griseus [Animal]

FamilyFusion protein

Tax ID9606;10029

Structure & Mods

Configlinear multidomain protein biologic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Immunomodulatory Immunosuppressive Anti-inflammatory

Half-Life270 h