Peptide Database

Peptide NameUnnamed

Function Ontology

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Standard StatusStandard

Sequence Length16 amino acids

Chemical FormulaC92H176N26O18

DescriptionStandard

        KTVLLRKLLKLLVRKI
    

Molecular Weight1934.55 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)5.76

Net Charge (pH 7.4) 5.55

Charge Density (pH 7.0) 0.3598

GRAVY Index0.65

Hydrophobic Moment 0.86

Boman Index-0.08

Instability Index0.19

Aliphatic Index 206.88

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 747.93

LogP -1.27

H-bond Donors 28.0

H-bond Acceptors 24.0

Rotatable Bonds 72.0

Heavy Atoms 136.0

Ring Count 0.0

Amide Bonds 15.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0199212 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermFluorescein-labelled

C-TermAmidation

Other ModsN-terminal fluorescein label; C-terminal amidation

Bio-Activity Profile

Function

Drug Delivery Vehicle Cell-penetrating peptide

TargetHuman Bowes melanoma cells; SH-SY5Y and N2A cells

Activityapproximately 5-10 fold intracellular concentration versus penetratin

Methodquantitative fluorescence uptake assay

RECORD: Rec_0199605 VERIFIED: YES

Provenance & Taxonomy

OrganismSynthetic construct [Synthetic]

FamilyDesigned synthetic CPP

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermFluorescein-labelled

C-TermAmidation

Other ModsN-terminal fluorescein label; C-terminal amidation

Bio-Activity Profile

Function

Cell-penetrating peptide

TargetHuman Bowes melanoma cells; SH-SY5Y and N2A cells

Activityapproximately 5-10 fold intracellular concentration versus penetratin

Methodquantitative fluorescence uptake assay

RECORD: Rec_0398548 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyE162

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermFluorescein-labelled

C-TermAmidation

Other ModsN-terminal fluorescein label; C-terminal amidation

Bio-Activity Profile

Function

Cell-penetrating peptide Cargo delivery

TargetHuman Bowes melanoma cells; SH-SY5Y and N2A cells

Activityapproximately 5-10 fold intracellular concentration versus penetratin

Methodquantitative fluorescence uptake assay