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MYP_123501
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Basic Information
Unnamed
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
20 amino acids
C117H175N23O23S2
Standard
Sequence
FLPFLLSALPKVFCFFSKKC
Physicochemical Analysis
2335.91 Da
9.39
2.74
2.50
0.1369
1.19
0.53
0.39
34.15
97.50
0.2500
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
717.16
-0.07
26.0
28.0
72.0
165.0
7.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0164865 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Brevinin
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Human erythrocytes
3 μM
HC50
Paperhttps://pubmed.ncbi.nlm.nih.gov/22943778/ PMID22943778 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22943778/
RECORD: Rec_0191876 VERIFIED: YES
Provenance & Taxonomy
Rana zhenhaiensis [Animal]
Brevinin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Escherichia coli ATCC 25922
16 μM
MIC
PMID22943778 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22943778/
RECORD: Rec_0255357 VERIFIED: YES
Provenance & Taxonomy
Rana zhenhaiensis [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 25922
16 μM
MIC
PMID22943778 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22943778/
RECORD: Rec_0355028 VERIFIED: YES
Provenance & Taxonomy
Rana zhenhaiensis [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans ATCC 2002
43 μM
MIC
PMID22943778 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22943778/
RECORD: Rec_0395245 VERIFIED: YES
Provenance & Taxonomy
Rana zhenhaiensis [Animal]
Brevinin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Staphylococcus aureus ATCC 2592
8 μM
MIC
PMID22943778 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22943778/
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