Peptide Database

Peptide NameDEFENSIN domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length120 amino acids

Chemical FormulaC566H928N156O180S9

DescriptionStandard

        MRTLALLAALLLLALQAQAGPLQERAEEAPKQEQPDTEDQDMAISFAGDESLAAGSTRGLTCYCRTGRCRLLERIYGSCIYAAPRTESNELIMCCETSTELLLLLPLVPHFLSSSQIKPS
    

Molecular Weight13086.95 Da

Isoelectric Point (pI)4.80

Net Charge (pH 7.0)-5.44

Net Charge (pH 7.4) -5.82

Charge Density (pH 7.0) -0.0453

GRAVY Index-0.01

Hydrophobic Moment 0.72

Boman Index0.04

Instability Index48.79

Aliphatic Index 98.58

Aromaticity 0.0417

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5369.66

LogP -55.83

H-bond Donors 191.0

H-bond Acceptors 185.0

Rotatable Bonds 434.0

Heavy Atoms 911.0

Ring Count 13.0

Amide Bonds 127.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0047676 VERIFIED: NO

Provenance & Taxonomy

OrganismProlemur simus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Antifungal Fungicide Non-hemolytic Non-ribosomal

MethodQualitative functional evidence