Peptide Database

Peptide NamePalustrin-1c

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length68 amino acids

Chemical FormulaC329H559N87O100S5

DescriptionStandard

        MFTTKKSLLLLFFLGTISLSLCEEERGADEEEGDGEKLTKRALSILRGLEKLAKMGIALTNCKATKKC
    

Molecular Weight7493.81 Da

Isoelectric Point (pI)8.52

Net Charge (pH 7.0)1.49

Net Charge (pH 7.4) 1.20

Charge Density (pH 7.0) 0.0219

GRAVY Index-0.08

Hydrophobic Moment 0.84

Boman Index-0.01

Instability Index30.55

Aliphatic Index 99.12

Aromaticity 0.0441

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3051.29

LogP -27.52

H-bond Donors 111.0

H-bond Acceptors 107.0

Rotatable Bonds 270.0

Heavy Atoms 521.0

Ring Count 3.0

Amide Bonds 68.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0039426 VERIFIED: YES

Provenance & Taxonomy

OrganismLithobates palustris [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Anti-Gram-negative Non-hemolytic

TargetGram Negative Bacteria