Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length457 amino acids

Chemical FormulaC2289H3601N621O632S12

DescriptionStandard

        TNPGFVVRITQAGLDYAHQQGITILEKELAQLKLPDISGDFRIRHVGKLRYDISSLDLRSFHLPHSRISLVPGVGLQVSISNAFAEVDGNWRVKLHFIRDHGSFDLEAEDVYIKIDLKLGSDATGKPTIDTSDCTTHISRVRVHFSGKFGWLYNLFYSAVEPMFRRSLEREVCDTVARSVRGELQPYLQTLPVTARIGAMAGIDYSLVAAPAATAQSLDAGLKGEFFSLAHRSAVPFPPLALALPPDHDRMVYFGASSYFFNTAGFAYHAAGVLVFEVTDSMVVSPRDGGLCRCPHPLPAPLQLEKIYPDMAMKLRLSAPSAPFLSIGPEGLSLRPVVDIQAYAILPNSSLAPLFLLSLTGNVSAVVGVRSGRIVGSLEVGRLKFFFLLPPLSAPQVRMLQSIMNTIASSVLLPRLNDRLDRGFPLPLPDRIQLSNILVRFHQNFLLLGADVRYYPR
    

Molecular Weight50316.64 Da

Isoelectric Point (pI)8.95

Net Charge (pH 7.0)5.53

Net Charge (pH 7.4) 4.55

Charge Density (pH 7.0) 0.0121

GRAVY Index0.14

Hydrophobic Moment 0.80

Boman Index0.12

Instability Index38.52

Aliphatic Index 103.70

Aromaticity 0.0919

Extinction Coeff. Reduced 31860.00

Extinction Coeff. Oxidized 32110.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0220145 VERIFIED: NO

Provenance & Taxonomy

OrganismCorythaeola cristata [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria