Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length123 amino acids

Chemical FormulaC620H966N162O183S10

DescriptionStandard

        MNLLILTFMICGLLNLVTKAGWFVERCWKNDVGYCRKRCLHLERYKLLCMNKLSCCIPLSSDNPYTQWPIRPTFGEDVTFGFGTHDGFPFSPISGLDDEVTIKTTKTQETTVTGTTASERDST
    

Molecular Weight13937.93 Da

Isoelectric Point (pI)6.70

Net Charge (pH 7.0)-0.38

Net Charge (pH 7.4) -0.83

Charge Density (pH 7.0) -0.0031

GRAVY Index-0.16

Hydrophobic Moment 0.58

Boman Index0.04

Instability Index33.07

Aliphatic Index 76.02

Aromaticity 0.1057

Extinction Coeff. Reduced 20970.00

Extinction Coeff. Oxidized 21345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5531.56

LogP -53.53

H-bond Donors 201.0

H-bond Acceptors 195.0

Rotatable Bonds 452.0

Heavy Atoms 975.0

Ring Count 24.0

Amide Bonds 129.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0203369 VERIFIED: NO

Provenance & Taxonomy

OrganismDelphinapterus leucas [Animal]

FamilyDefensin

Tax ID9749

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence