Peptide Database

Peptide NamePyocin-S2 (EC 3.1.-.-)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length513 amino acids

Chemical FormulaC2470H3843N703O771S20

DescriptionStandard

        MPRMLACLGNKTTKGTIIHASSTLFEGSHPLARDGDLAWCNECKNSFPMLGTATSIIDDRPMVAFGDKVLCRCSDHWVIAQSTWFCEHQDSGKESTITNQQSFTQSNPPSLAELSYTDNSPSVETVFAKSCLLSDGCTDAGQEQEPVENFGEVSLFQGTDIECGYRCEPSPSPQITSVGALIASQTGIRVLQHSAGTSIAGRWMVSNPISILLIGLFYSPEISQGSHRDGLADYIARDKLDYLATTGGTATTRVRFQARVNIQTNQPVIEGYHTPANSELDQVPVIKMRLDSSNGIRRYIPEGQSGPSIIWTPAEPEYSPINHTGNHSGYSAPLSILVNPLPETPGDHSTTSPIPEKKNFNDYILVFPADSGMPPIYIMLDSPRNESGVVIGQGETIFGTWLRDAGAGLGCPVPAQIADKLRGREFTNFDQFREAFWIEVSKDAELSSQFIPSNRKKMANGRAPRARYRDTVGGRRSFELHHKHQIQHGGNVYDVENLNVVTPKRHIDIHRDN
    

Molecular Weight56363.48 Da

Isoelectric Point (pI)5.74

Net Charge (pH 7.0)-11.13

Net Charge (pH 7.4) -12.43

Charge Density (pH 7.0) -0.0217

GRAVY Index-0.42

Hydrophobic Moment 0.63

Boman Index-0.00

Instability Index49.93

Aliphatic Index 74.15

Aromaticity 0.0760

Extinction Coeff. Reduced 57870.00

Extinction Coeff. Oxidized 58495.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0063189 VERIFIED: NO

Provenance & Taxonomy

OrganismPragia fontium [Bacterium]

FamilyColicin/Bacteriocin

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Hydrolase Non-hemolytic

TargetEscherichia coli (Gram-negative)

MethodQualitative functional evidence