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MYP_123426
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Basic Information
Brevinin-1AUb (Frogs, amphibians, animals)
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
24 amino acids
C121H202N28O28S2
Standard
Sequence
FLPILAGLAANILPKVFCSITKKC
Physicochemical Analysis
2561.20 Da
9.39
2.74
2.50
0.1141
1.19
0.59
0.40
56.45
138.33
0.0833
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
876.65
-3.79
31.0
33.0
82.0
179.0
4.0
24.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0055654 VERIFIED: YES
Provenance & Taxonomy
Rana aurora [Animal]
Brevinin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
18-24
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Klebsiella pneumoniae
50 μM
MIC
PMID15325526 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15325526/
RECORD: Rec_0062652 VERIFIED: YES
Provenance & Taxonomy
Rana aurora aurora [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli
25 μM
MIC
PMID15325526 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15325526/
RECORD: Rec_0064452 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Toxic Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0065470 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Human erythrocytes
7 μM
HC50
Paperhttps://pubmed.ncbi.nlm.nih.gov/15325526/ PMID15325526 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15325526/
RECORD: Rec_0068753 VERIFIED: YES
Provenance & Taxonomy
Rana aurora aurora [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Streptococcus Group B HNTCC80130
13 μM
MIC
PMID15325526 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15325526/
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