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MYP_123417
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Basic Information
PenArg
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
16 amino acids
C104H168N42O20S
Standard
Sequence
RQIRIWFQNRRMRWRR
Physicochemical Analysis
2358.78 Da
12.00
6.76
6.56
0.4225
-1.88
0.47
-0.87
124.10
48.75
0.1875
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1093.97
-8.54
43.0
28.0
80.0
167.0
5.0
18.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0055547 VERIFIED: YES
Provenance & Taxonomy
Drosophila melanogaster [Animal]
Penetratin
7227
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Unknown
Unknown
Bio-Activity Profile
Cell-penetrating peptide
PMID18045726 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18045726/
RECORD: Rec_0083261 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus(ATCC 33591)
16 μM
MIC
PaperPubMed PMID: 23085001 PMID23085001 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23085001/
RECORD: Rec_0092450 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
PenArg
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Fluorescein/FITC labeling
Amidation
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PMID12849987 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12849987/
RECORD: Rec_0165210 VERIFIED: YES
Provenance & Taxonomy
Drosophila melanogaster [Animal]
Penetratin
7227
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Fluorescein/FITC labeling
Amidation
N-term detail: Labeled with fluorescein
Bio-Activity Profile
Cell-penetrating peptide
PC-12; V79 cells
Fluorescence-based uptake assay
PMID12849987 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12849987/
RECORD: Rec_0174329 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
PenArg
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PMID22281502 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22281502/
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