Peptide Database

Peptide NamePancreatic polypeptide

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Neuropeptide Y family

Standard StatusStandard

Sequence Length36 amino acids

Chemical FormulaC191H294N52O58S

DescriptionStandard

        YPPKPENPGEDASPEEMTKYLTALRHYINLVTRQRY
    

Molecular Weight4278.76 Da

Isoelectric Point (pI)6.77

Net Charge (pH 7.0)-0.15

Net Charge (pH 7.4) -0.42

Charge Density (pH 7.0) -0.0041

GRAVY Index-1.21

Hydrophobic Moment 0.71

Boman Index-0.22

Instability Index72.78

Aliphatic Index 56.94

Aromaticity 0.1111

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 5960.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1781.90

LogP -15.95

H-bond Donors 60.0

H-bond Acceptors 60.0

Rotatable Bonds 133.0

Heavy Atoms 302.0

Ring Count 10.0

Amide Bonds 38.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0009989 VERIFIED: YES

Provenance & Taxonomy

OrganismPelophylax ridibundus [Animal]

FamilyNPY

Tax ID8406

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

NPY-family Neuropeptide Neuromodulator

RECORD: Rec_0231433 VERIFIED: YES

Provenance & Taxonomy

OrganismPelophylax ridibundus [Animal]

FamilyPeptide YY-like

Tax ID8406

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Hormone Endocrine

Half-LifeMammalian: 2.8 hour; Yeast: 10 min; E. coli: 2 min

RECORD: Rec_0365865 VERIFIED: NO

Provenance & Taxonomy

OrganismRana ridibunda [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Hormone

RECORD: Rec_0421440 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyNeuropeptide Y / neuropeptide F

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/