Peptide Database

Peptide NameNattererin-1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length30 amino acids

Chemical FormulaC143H243N39O40S

DescriptionStandard

        GLKDMIKNLAKEAAVKLAGAVINKFSPQPQ
    

Molecular Weight3180.76 Da

Isoelectric Point (pI)9.83

Net Charge (pH 7.0)2.76

Net Charge (pH 7.4) 2.55

Charge Density (pH 7.0) 0.0920

GRAVY Index-0.09

Hydrophobic Moment 0.70

Boman Index0.06

Instability Index39.19

Aliphatic Index 101.00

Aromaticity 0.0333

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1286.93

LogP -11.37

H-bond Donors 41.0

H-bond Acceptors 44.0

Rotatable Bonds 110.0

Heavy Atoms 223.0

Ring Count 3.0

Amide Bonds 33.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0384554 VERIFIED: YES

Provenance & Taxonomy

OrganismPhysalaemus nattereri [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-negative

TargetEscherichia coli

Activity10 μM

MethodMIC

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