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MYP_123287
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Basic Information
D-Cathelicidin-1 [V6,7,10w], D-Bactenecin-1 [V6,7,10w]
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
12 amino acids
C81H123N27O13S2
Standard
Sequence
RLCRIWWIRWCR
Physicochemical Analysis
1747.15 Da
11.53
3.74
3.51
0.3117
-0.24
0.38
-0.27
56.90
97.50
0.2500
16500.00
16625.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
678.39
-1.05
30.0
19.0
53.0
123.0
6.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0300268 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus KCCM 40510
16-32 μM
MIC
PMID31056261 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31056261/
RECORD: Rec_0304316 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
3-11
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa
4 μM
MIC
PMID31056261 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31056261/
RECORD: Rec_0323601 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
3-11
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus epidermidis
8 μM
MIC
PMID31056261 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31056261/
RECORD: Rec_0344978 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
3-11
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Gram-positive bacteria: Staphylococcus aureus
16 μM
MIC
PMID31056261 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31056261/
RECORD: Rec_0401784 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
Bio-Activity Profile
Hemolytic
human red blood cells
0.9 %
Hemolysis
PMID31056261 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31056261/
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