Peptide Database

Peptide NamePyocin large subunit

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length197 amino acids

Chemical FormulaC985H1467N271O287S3

DescriptionStandard

        MIVADIHSPRKPQPYRWLWAGLAQVWGEWPLSGTLSATRAIPYVGALASALYISSAGEGSARVPGRDEYWYEEALRQKALTGSTATTRVRFFWGTDTHGAPQVYGVHTGEGTPYENVRVANMVWNDEHHRYEFTPAHDIDGPLITWTPENPVNGDLPNHTGSNVPPLDQPTILVTPIPDGKNEYTTPPFPGAGCRRF
    

Molecular Weight21793.02 Da

Isoelectric Point (pI)5.76

Net Charge (pH 7.0)-4.87

Net Charge (pH 7.4) -5.50

Charge Density (pH 7.0) -0.0247

GRAVY Index-0.49

Hydrophobic Moment 0.50

Boman Index0.05

Instability Index19.78

Aliphatic Index 67.36

Aromaticity 0.1117

Extinction Coeff. Reduced 57410.00

Extinction Coeff. Oxidized 57410.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8764.72

LogP -102.83

H-bond Donors 301.0

H-bond Acceptors 292.0

Rotatable Bonds 659.0

Heavy Atoms 1546.0

Ring Count 58.0

Amide Bonds 209.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0206383 VERIFIED: YES

Provenance & Taxonomy

OrganismCitrobacter koseri [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)