Peptide Database

Peptide NameSodium/potassium ATPase inhibitor SPAI-1

Function Ontology

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length49 amino acids

Chemical FormulaC245H386N72O65S8

DescriptionStandard

        LLSKRGHCPRILFRCPLSNPSNKCWRDYDCPGVKKCCEGFCGKDCLYPK
    

Molecular Weight5636.65 Da

Isoelectric Point (pI)9.05

Net Charge (pH 7.0)5.77

Net Charge (pH 7.4) 5.38

Charge Density (pH 7.0) 0.1177

GRAVY Index-0.57

Hydrophobic Moment 0.57

Boman Index-0.18

Instability Index50.87

Aliphatic Index 53.67

Aromaticity 0.1020

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2200.89

LogP -20.99

H-bond Donors 84.0

H-bond Acceptors 80.0

Rotatable Bonds 181.0

Heavy Atoms 390.0

Ring Count 12.0

Amide Bonds 50.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0307935 VERIFIED: NO

Provenance & Taxonomy

OrganismSus scrofa [Animal]

Tax ID9823

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide8-37; 15-41; 24-36; 30-45

Bio-Activity Profile

Function

Enzyme inhibitory