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MYP_123222
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Basic Information
Gaegurin-5
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
24 amino acids
C122H200N28O28S2
Standard
Sequence
FLGALFKVASKVLPSVFCAITKKC
Physicochemical Analysis
2571.19 Da
9.70
3.74
3.50
0.1557
1.14
0.57
0.33
8.76
113.75
0.1250
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
888.60
-4.63
33.0
34.0
84.0
180.0
4.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0385834 VERIFIED: YES
Provenance & Taxonomy
Rana rugosa [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
18-24
Bio-Activity Profile
Antimicrobial Antifungal Antiparasitic
Staphylococcus epidermidis
10 μg/mL
MIC
PaperAntimicrobial peptides from the skin of a Korean frog, Rana rugosa.
RECORD: Rec_0390542 VERIFIED: YES
Provenance & Taxonomy
Glandirana rugosa [Animal]
Gaegurin
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
18-24
Bio-Activity Profile
Antimicrobial Antibacterial Anticancer
PaperH-S. Won et al. / Biochimica et Biophysica Acta 1788 (2009) 1620-1629. Action mechanism and structural requirements of the antimicrobial peptides, gaegurins Evidence URLhttps://www.uniprot.org/uniprotkb/P80399/entry
RECORD: Rec_0406214 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 41.7%, E 0.0%, T 33.3%, C 25.0% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antiparasitic Antimicrobial Antifungal Anti-Gram-positive Anti-Gram-negative
PaperDADP: the database of anuran defense peptides PMID22467909 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22467909/
RECORD: Rec_0427354 VERIFIED: YES
Provenance & Taxonomy
Rana rugosa [Animal]
Gaegurin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Antiparasitic Antiprotozoal Anti-Gram-positive Anti-Gram-negative
Pseudomonas putida
50 μg/mL
MIC
PMID7999137 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7999137/
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