Peptide Database

Peptide Namecliotide T6

Function Ontology

Antimicrobial

Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length30 amino acids

Chemical FormulaC131H211N33O44S6

DescriptionStandard

        SIPCGESCVYIPCLTTIVGCSCKNSVCYSN
    

Molecular Weight3144.66 Da

Isoelectric Point (pI)5.71

Net Charge (pH 7.0)-0.60

Net Charge (pH 7.4) -0.90

Charge Density (pH 7.0) -0.0200

GRAVY Index0.62

Hydrophobic Moment 0.32

Boman Index0.24

Instability Index24.09

Aliphatic Index 81.00

Aromaticity 0.0667

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1221.21

LogP -16.17

H-bond Donors 48.0

H-bond Acceptors 50.0

Rotatable Bonds 96.0

Heavy Atoms 214.0

Ring Count 4.0

Amide Bonds 31.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0369826 VERIFIED: YES

Provenance & Taxonomy

OrganismClitoria ternatea [Plant]

FamilyCyclotide

Tax ID43366

Structure & Mods

Confighead-to-tail cyclic peptide scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

DisulfideCysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family

Bio-Activity Profile

Function

Antimicrobial Enzyme inhibitory Immunomodulatory Enzyme-inhibitory ACE inhibitory Antihypertensive

TargetAngiotensin-converting enzyme