Peptide Database

Peptide NameSLAY-screened peptide P2915

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC107H173N29O27S

DescriptionStandard

        PNTSIVLCHLSRAIYLYRLP
    

Molecular Weight2329.76 Da

Isoelectric Point (pI)9.37

Net Charge (pH 7.0)2.03

Net Charge (pH 7.4) 1.91

Charge Density (pH 7.0) 0.1017

GRAVY Index0.45

Hydrophobic Moment 0.49

Boman Index0.15

Instability Index28.11

Aliphatic Index 136.50

Aromaticity 0.1000

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 890.16

LogP -5.95

H-bond Donors 34.0

H-bond Acceptors 31.0

Rotatable Bonds 71.0

Heavy Atoms 164.0

Ring Count 5.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0221533 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/