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MYP_123087
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Basic Information
Caerin-1.17 [Cleaved into: Caerin-1.17.1; Caerin-1.17.2]
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
25 amino acids
C124H205N31O30
Standard
Sequence
GLFSVLGSVAKHLLPHVAPIIAEKL
Physicochemical Analysis
2610.14 Da
8.61
0.94
0.63
0.0374
1.02
0.47
0.43
21.61
156.00
0.0400
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
931.30
-4.06
31.0
33.0
83.0
185.0
5.0
24.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0197933 VERIFIED: YES
Provenance & Taxonomy
Litoria gracilenta [Animal]
Caerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus cereus
100 μg/mL
MIC
PMID16554081 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16554081/
RECORD: Rec_0250922 VERIFIED: YES
Provenance & Taxonomy
Litoria gracilenta [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0271924 VERIFIED: YES
Provenance & Taxonomy
Litoria gracilenta [Animal]
Caerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus Strain ATCC 25923
50 μg/mL
MIC
PMID16554081 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16554081/
RECORD: Rec_0283999 VERIFIED: YES
Provenance & Taxonomy
Litoria gracilenta [Animal]
Caerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Listeria innocua
25 μg/mL
MIC
PMID16554081 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16554081/
RECORD: Rec_0300272 VERIFIED: YES
Provenance & Taxonomy
Litoria gracilenta [Animal]
Caerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Pasteurella multocida
25 μg/mL
MIC
PMID16554081 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16554081/
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