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MYP_123061
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Basic Information
Dermaseptin t-DPH1 [S4K,A11A]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
21 amino acids
C98H170N28O23
Standard
Sequence
GLWKKIKNVAKAAGKAALGAL
Physicochemical Analysis
2108.57 Da
10.60
4.76
4.54
0.2264
0.28
0.68
0.16
4.63
116.67
0.0476
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
834.30
-5.81
29.0
28.0
74.0
149.0
2.0
21.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0005787 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID34943741 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34943741/
RECORD: Rec_0016973 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Methicillin-resistant Staphylococcus aureus
2 μM
MIC
PMID34943741 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34943741/
RECORD: Rec_0021351 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa ATCC 9027
4 μM
MIC
PMID34943741 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34943741/
RECORD: Rec_0054701 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
PMID34943741 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34943741/
RECORD: Rec_0073492 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 6538
2 μM
MIC
PMID34943741 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34943741/
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