Peptide Database

Peptide NameBeta-defensin 14 (BD-14) (mBD-14) (Defensin; beta 14)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length67 amino acids

Chemical FormulaC348H571N103O81S7

DescriptionStandard

        MRLHYLLFVFLILFLVPAPGDAFLPKTLRKFFCRIRGGRCAVLNCLGKEEQIGRCSNSGRKCCRKKK
    

Molecular Weight7718.35 Da

Isoelectric Point (pI)10.26

Net Charge (pH 7.0)11.53

Net Charge (pH 7.4) 11.16

Charge Density (pH 7.0) 0.1720

GRAVY Index0.07

Hydrophobic Moment 0.76

Boman Index-0.05

Instability Index42.02

Aliphatic Index 93.13

Aromaticity 0.1045

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2985.66

LogP -22.37

H-bond Donors 113.0

H-bond Acceptors 101.0

Rotatable Bonds 262.0

Heavy Atoms 539.0

Ring Count 11.0

Amide Bonds 69.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0137318 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyBeta-defensin; Defensin

Tax ID10090

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic

RECORD: Rec_0380581 VERIFIED: NO

Provenance & Taxonomy

OrganismMus spicilegus [Animal]

FamilyDefensin

Tax ID10103

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal