Peptide Database

Peptide NamePyocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length567 amino acids

Chemical FormulaC2773H4369N815O829S24

DescriptionStandard

        MTYRPDIHGRGMALSCDKTTTGAWLITSLPVPNYNVCGYGLIRKGDKTTPCPACGKPGMVAEGEARFKVIDIPIAVDGCVVHCGCPEGSNRIRAPLGQWMGAGPSPAEIAQKKQAELIAQRRAEREAEEKRREEERERNRVFAKSCLRGEGCNDAGDQREPHTNFAPMGIYQAVPQTDPVTDTEAPQRAQAVKKKKLIAPEDIPKPKKRSALWKWWNGHHEEMDYQRAVEEAERAQRARAAIAGASVLHPVAGNFAIRGTWAVVGETATGVAGLPLAAFLIGMMPGRLNDGEQDFIDRMRAEQAREVPTRVRFTWETNSRGNPVPHGWHTPPGQDRVRVRRMEWDDRRKAYTFTTEEDPRITLIWTPDNPGIDVPNHTGNQYPPVLPNPVMVDPLPDDTGLHATTSPAPEERDFADYILILPFPDIPPIYIYLSKPPVEFLEVELYSDFKRRSRQGKYEADHMPSAAAVKAYIKANYPGMTPEDIELASRDVAAIVIPKEVHQKMSETYGGRNTPAQIDLDSRNLRAAADRNLDAIKPALKEHGATENQIEAARTKIHELNSKMGLY
    

Molecular Weight63157.88 Da

Isoelectric Point (pI)6.73

Net Charge (pH 7.0)-1.25

Net Charge (pH 7.4) -2.47

Charge Density (pH 7.0) -0.0022

GRAVY Index-0.63

Hydrophobic Moment 0.77

Boman Index-0.10

Instability Index42.86

Aliphatic Index 69.95

Aromaticity 0.0670

Extinction Coeff. Reduced 78840.00

Extinction Coeff. Oxidized 79340.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0240812 VERIFIED: YES

Provenance & Taxonomy

OrganismEscherichia coli [Bacterium]

FamilyPyocin/Colicin

Tax ID562

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Non-hemolytic Non-ribosomal

TargetEscherichia coli